What is TIVDAK? TIVDAK is a prescription medicine used to treat adults with cervical cancer that has returned or has spread to other parts of the body, and who have received chemotherapy that did not work or is no longer working.

RESOURCES TO HELP YOU WHILE ON TREATMENT

There are several useful resources available to help you while on Tivdak

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Patient Brochure

An overview of Tivdak and what to expect from treatment

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Image sample from the first page of the Tivdak® (tisotumab vedotin-tftv) Caregiver Brochure

Caregiver Brochure

A resource providing guidance to caregivers about supporting their loved ones on Tivdak

Download English
Download Español
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TivdakTexts Brochure

A guide to a text message support program designed to assist you throughout treatment

Download English
Image sample from the first page of the Tivdak (tisotumab vedotin-tftv) Important Facts document
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Important Facts

A short summary of key information about Tivdak

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SEAGEN SECURE®

Need help with access and out-of-pocket costs?

Seagen Secure® logo

Seagen Secure® offers support to enrolled patients*

Seagen Secure® is a personalized support program for people prescribed Tivdak. When you or your caregiver calls Seagen Secure®, you will speak with an Oncology Access Advocate who can answer your questions and provide information about available resources and support.

Seagen Secure® may be able to help if you:

  • Don’t have any health insurance
  • Aren’t sure if your insurance will cover your therapy
  • Need assistance paying patient out-of-pocket costs

*Eligibility criteria apply. Financial support may be provided through third-party organizations that have their own eligibility criteria and enrollment processes. Pfizer does not guarantee that enrollment will result in assistance and/or reimbursement.

Information provided by an Oncology Access Advocate is not intended to be a substitute for clinical advice from your healthcare provider. Discuss any questions you may have about your disease and your treatment with your healthcare team.

Seagen Secure® programs available for qualifying patients. Pfizer does not guarantee that enrollment will result in coverage, reimbursement, or financial support.

Call 855-4SECURE (855-473-2873) to learn how to enroll in Seagen Secure®

Visit the Website

Download the Brochure

TivdakTexts

Sign up for TivdakTexts

TivdakTexts is a free text message support program designed to assist you throughout treatment§

Some benefits of TivdakTexts include:

  • Calendar icon

    Infusion reminders

  • Droplet icon

    Eye drop reminders

  • Cell phone icon

    Inspirational messages

Cell phone showing a text message. The text message reads: Welcome to the Tivdak (tisotumab vedotin-tftv)Text program! With this program, you’ll receive important infusion and eye care reminders during your treatment with Tivdak (tisotumab vedotin-tftv) (tisotumab vedotin-tftv) for injection 40mg

To sign up for TivdakTexts, you can follow these steps:

  • Step 1

    On your mobile phone, text the word JOIN to 74277

  • Step 2

    When you get a message back from us, text back AGREE to confirm your participation in the support program

  • Step 3

    Then provide the following information:

    • Your first name so we can personalize messages
    • Your ZIP Code so we can set your time zone
    • The timing of your upcoming Tivdak infusion

§Message and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP for help with the program. Text STOP to stop receiving messages. See Terms of Use and Conditions. By initiating a text message, you agree to receive automated text messages from Pfizer. You can unsubscribe at any time. You represent that you are the subscriber of the number provided and 18 or older. You must notify Pfizer immediately if you relinquish the number provided. Consent is not required as a condition of purchasing any products or services.

Find an eye specialist

Find an eye specialist

An eye specialist will help monitor your eye health throughout treatment. Use this locator tool to find one near you.

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Advocacy groups

Help is out there

When you have advanced cancer, it can be hard to know where to turn. There are a number of groups offering care and support throughout your experience.

These patient support groups are included as a reference for patients and caregivers. Their inclusion does not imply endorsement from the individual patient support groups listed.

Cancer Support Community logo

Cancer Support Community

A worldwide network committed to ensuring that no one faces cancer alone by providing navigation, support, and resources through face-to-face, telephone, and online programming.

cancersupportcommunity.org

Cervivor logo

Cervivor

A cervical cancer awareness and support community, a learning tool, an advocacy resource, and an online retreat for healing, connecting, and thriving.

cervivor.org

Family Reach logo

Family Reach

Family Reach delivers financial education, financial coaching, resource navigation, and emergency relief to patients and caregivers facing a cancer diagnosis.

familyreach.org

Foundation for Women’s Cancer logo

Foundation for Women’s Cancer

A foundation dedicated to increasing research, education, and awareness about gynecologic cancer risk, prevention, early detection, and optimal treatment.

foundationforwomenscancer.org

National Cervical Cancer Coalition, A program of the American Sexual Health Association logo

National Cervical Cancer Coalition

A grassroots organization that helps women, family members, and caregivers battle the personal issues related to cervical cancer and HPV, and advocates for cervical health in all women.

nccc-online.org

Triage Cancer logo

Triage Cancer

A nonprofit group that provides education on the practical and legal issues that may impact individuals diagnosed with cancer and their caregivers through free events, materials, and resources.

triagecancer.org

By clicking these links, you will be redirected to websites that are neither owned nor controlled by Pfizer or Genmab. Pfizer and Genmab are not responsible for the content or services of these sites.

Hear a real Tivdak PATIENT’S STORY

Alisha, a Tivdak® (tisotumab vedotin-tftv) patient.

What to expect DURING TREATMENT

Woman looking at the camera

See the STUDY RESULTS

Woman using a tablet.

Important Safety Information

What is the most important information I should know about TIVDAK?

Eye problems are common with TIVDAK and can be severe. TIVDAK can cause changes to the surface of your eye that can lead to dry eyes, eye redness, eye irritation, corneal ulcers, blurred vision, and severe vision loss. Tell your healthcare provider if you develop new or worsening vision changes or eye problems during treatment.

Your healthcare provider will send you to an eye specialist to check your eyes before you start treatment with TIVDAK, before each infusion for your first 9 infusions of TIVDAK, and as needed for any new or worsening signs or symptoms of eye problems. Your healthcare provider will ask if you have any signs or symptoms of eye problems before each infusion. You will be referred to an eye specialist for any new or worsening signs or symptoms of eye problems.

Your healthcare provider will prescribe 3 different types of eye drops before you start treatment with TIVDAK. Bring the eye drops with you to each infusion and use them as directed by your healthcare provider to reduce your risk of eye problems:

  • Use 1 drop of steroid eye drops in each eye before each infusion and continue to use your eye drops 3 times a day for 3 days after each infusion
  • Use vasoconstrictor eye drops right before each infusion
  • Use lubricating eye drops throughout treatment and for 30 days after your last dose of TIVDAK

Do not wear contact lenses throughout your treatment with TIVDAK unless you are told to use them by your eye specialist.

What are the possible side effects of TIVDAK?

Serious side effects of TIVDAK may include:

Eye problems. See “What is the most important information I should know about TIVDAK?”

Nerve problems (peripheral neuropathy) are common with TIVDAK and can be serious. Tell your healthcare provider right away if you have new or worsening numbness or tingling in your hands or feet or muscle weakness.

Bleeding problems (hemorrhage) are common with TIVDAK and can be serious. Tell your healthcare provider or get medical help right away if you have signs or symptoms of bleeding during treatment with TIVDAK, including blood in your stools or black stools (looks like tar), blood in your urine, cough up or vomit blood, unusual vaginal bleeding, or any unusual or heavy bleeding.

Lung problems. TIVDAK may cause severe or life-threatening inflammation of the lungs that can lead to death. Tell your healthcare provider right away if you have new or worsening symptoms, including trouble breathing, shortness of breath, or cough.

Severe skin reactions. TIVDAK may cause severe or life-threatening skin reactions that can lead to death. Tell your healthcare provider or get medical help right away if you have signs or symptoms of a severe skin reaction during treatment with TIVDAK, including:

  • Skin reactions that look like rings (target lesions)
  • Rash or itching that continues to get worse
  • Blistering or peeling of the skin
  • Painful sores or ulcers in your mouth, nose, throat, or genital area
  • Fever or flu-like symptoms
  • Swollen lymph nodes

The most common side effects of TIVDAK include:

  • Decreased red blood cell counts
  • Numbness or tingling in your hands or feet
  • Eye problems (conjunctival disorders)
  • Nausea
  • Tiredness
  • Changes in liver function blood tests
  • Nosebleed
  • Hair loss (alopecia)
  • Bleeding (hemorrhage)

Your healthcare provider may decrease your dose of TIVDAK, temporarily stop, or completely stop treatment if you have side effects.

What should I tell my healthcare provider before receiving TIVDAK?

Tell your healthcare provider about all your medical conditions, including if you:

  • have a history of vision or eye problems
  • have numbness or tingling in your hands or feet
  • have bleeding problems
  • have liver problems
  • are pregnant or plan to become pregnant; TIVDAK can harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with TIVDAK
  • are breastfeeding (nursing) or plan to breastfeed. It is not known if TIVDAK passes into your breast milk. Do not breastfeed during treatment and for at least 3 weeks after the last dose of TIVDAK

    Females who can become pregnant:

    • Your healthcare provider should do a pregnancy test before you start treatment with TIVDAK
    • Use an effective method of birth control during your treatment and for at least 2 months after the last dose of TIVDAK

    Males with female partners who can become pregnant:

    • Use effective birth control during treatment and for 4 months after the last dose of TIVDAK

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking TIVDAK with certain other medicines may cause side effects.

These are not all of the possible side effects of TIVDAK. Discuss side effects with your healthcare provider. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information with Medication Guide about TIVDAK including an IMPORTANT WARNING.

What is TIVDAK?

TIVDAK is a prescription medicine used to treat adults with cervical cancer:

  • that has returned or has spread to other parts of the body, and
  • who have received chemotherapy that did not work or is no longer working.

Important Safety Information

What is the most important information I should know about TIVDAK?

Eye problems are common with TIVDAK and can be severe. TIVDAK can cause changes to the surface of your eye that can lead to dry eyes, eye redness, eye irritation, corneal ulcers, blurred vision, and severe vision loss. Tell your healthcare provider if you develop new or worsening vision changes or eye problems during treatment.

Your healthcare provider will send you to an eye specialist to check your eyes before you start treatment with TIVDAK, before each infusion for your first 9 infusions of TIVDAK, and as needed for any new or worsening signs or symptoms of eye problems. Your healthcare provider will ask if you have any signs or symptoms of eye problems before each infusion. You will be referred to an eye specialist for any new or worsening signs or symptoms of eye problems.

Your healthcare provider will prescribe 3 different types of eye drops before you start treatment with TIVDAK. Bring the eye drops with you to each infusion and use them as directed by your healthcare provider to reduce your risk of eye problems:

  • Use 1 drop of steroid eye drops in each eye before each infusion and continue to use your eye drops 3 times a day for 3 days after each infusion
  • Use vasoconstrictor eye drops right before each infusion
  • Use lubricating eye drops throughout treatment and for 30 days after your last dose of TIVDAK

Do not wear contact lenses throughout your treatment with TIVDAK unless you are told to use them by your eye specialist.

What are the possible side effects of TIVDAK?

Serious side effects of TIVDAK may include:

Eye problems. See “What is the most important information I should know about TIVDAK?”

Nerve problems (peripheral neuropathy) are common with TIVDAK and can be serious. Tell your healthcare provider right away if you have new or worsening numbness or tingling in your hands or feet or muscle weakness.

Bleeding problems (hemorrhage) are common with TIVDAK and can be serious. Tell your healthcare provider or get medical help right away if you have signs or symptoms of bleeding during treatment with TIVDAK, including blood in your stools or black stools (looks like tar), blood in your urine, cough up or vomit blood, unusual vaginal bleeding, or any unusual or heavy bleeding.

Lung problems. TIVDAK may cause severe or life-threatening inflammation of the lungs that can lead to death. Tell your healthcare provider right away if you have new or worsening symptoms, including trouble breathing, shortness of breath, or cough.

Severe skin reactions. TIVDAK may cause severe or life-threatening skin reactions that can lead to death. Tell your healthcare provider or get medical help right away if you have signs or symptoms of a severe skin reaction during treatment with TIVDAK, including:

  • Skin reactions that look like rings (target lesions)
  • Rash or itching that continues to get worse
  • Blistering or peeling of the skin
  • Painful sores or ulcers in your mouth, nose, throat, or genital area
  • Fever or flu-like symptoms
  • Swollen lymph nodes

The most common side effects of TIVDAK include:

  • Decreased red blood cell counts
  • Numbness or tingling in your hands or feet
  • Eye problems (conjunctival disorders)
  • Nausea
  • Tiredness
  • Changes in liver function blood tests
  • Nosebleed
  • Hair loss (alopecia)
  • Bleeding (hemorrhage)

Your healthcare provider may decrease your dose of TIVDAK, temporarily stop, or completely stop treatment if you have side effects.

What should I tell my healthcare provider before receiving TIVDAK?

Tell your healthcare provider about all your medical conditions, including if you:

  • have a history of vision or eye problems
  • have numbness or tingling in your hands or feet
  • have bleeding problems
  • have liver problems
  • are pregnant or plan to become pregnant; TIVDAK can harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with TIVDAK
  • are breastfeeding (nursing) or plan to breastfeed. It is not known if TIVDAK passes into your breast milk. Do not breastfeed during treatment and for at least 3 weeks after the last dose of TIVDAK

    Females who can become pregnant:

    • Your healthcare provider should do a pregnancy test before you start treatment with TIVDAK
    • Use an effective method of birth control during your treatment and for at least 2 months after the last dose of TIVDAK

    Males with female partners who can become pregnant:

    • Use effective birth control during treatment and for 4 months after the last dose of TIVDAK

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking TIVDAK with certain other medicines may cause side effects.

These are not all of the possible side effects of TIVDAK. Discuss side effects with your healthcare provider. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information with Medication Guide about TIVDAK including an IMPORTANT WARNING.

What is TIVDAK?

TIVDAK is a prescription medicine used to treat adults with cervical cancer:

  • that has returned or has spread to other parts of the body, and
  • who have received chemotherapy that did not work or is no longer working.